diff --git a/litellm/llms/bedrock/messages/invoke_transformations/anthropic_claude3_transformation.py b/litellm/llms/bedrock/messages/invoke_transformations/anthropic_claude3_transformation.py
index 2c041adba7..477fa3316d 100644
--- a/litellm/llms/bedrock/messages/invoke_transformations/anthropic_claude3_transformation.py
+++ b/litellm/llms/bedrock/messages/invoke_transformations/anthropic_claude3_transformation.py
@@ -246,6 +246,11 @@ class AmazonAnthropicClaudeMessagesConfig(
             "sonnet_4.5",
             "sonnet-4-5",
             "sonnet_4_5",
+            # Opus 4.6
+            "opus-4.6",
+            "opus_4.6",
+            "opus-4-6",
+            "opus_4_6",
         ]
 
         return any(pattern in model_lower for pattern in supported_patterns)